CX3CR1

(redirected from Fractalkine receptor)

CX3CR1

A gene on chromosome 3p21.3 that encodes a G protein-coupled receptor for fractalkine, a transmembrane protein and chemokine involved in leukocyte adhesion and migration. CX3CR1 is also a coreceptor for HIV-1; some alternatively spliced forms of CX3CR1 lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS.
References in periodicals archive ?
Also, cancer cells that have the Fractalkine receptor on their surface migrate towards nerve ends that have Fractalkine on their surface.
In contrast, fractalkine had no effect in mice or islets when the fractalkine receptor was deleted.