folate deficiency

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folate deficiency

a deficiency of folic acid. See also folic acid.

folate deficiency

Folic acid deficiency Hematology A condition caused by a decrease in dietary folic acid, resulting in megaloblastic anermia, GI tract complaints–eg, glossitis, stomatitis, malabsorption, infertility, neural tube defects, and possibly also psychiatric complaints and peripheral neuropathy. See Megaloblastic anemia.
References in periodicals archive ?
Previous studies have demonstrated that poor appetite may lead to micronutrient deficiency, including iron or folic acid deficiency.
In conditions of folic acid deficiency, individual cells are more exposed to the risk of acquiring genetic abnormalities and if these abnormalities are not eliminated, they may lead to cancer later on.
12] Vitamin B12 or folic acid deficiency can both cause the Hcy level to rise.
KEY WORDS: Anemia, Vit B12 deficiency anemia, Folic acid deficiency.
Folic acid deficiency is associated with increased fetal NTDs and maternal megaloblastic anemia (7-11).
A central origin was evoked; however, the role of the folic acid deficiency could not explain the macrocytosis, the mechanism of which remains to be elucidated.
While at the hospital, he became aware of the high mortality rate among premature babies, a consequence of folic acid deficiency in the largely maize-based diet.
The anaemia of pregnancy is typically macrocytic, reflecting folic acid deficiency owing to increased demand exerted by the growing fetus.
Folic acid deficiency in fathers-to-be could also interfere with the genetic quality of sperms, possibly leading to Down syndrome.
Speaking of folic acid deficiency, low dietary intake of folate or genetic polymorphism alters the folate metabolism leading to the impaired purine and pyrimidine metabolism, DNA synthesis and/or cell proliferation; and affect foetal growth and result in teratogenesis and congenital malformations [7, 27].
In postulating reasons for the slightly increased number of birth defects seen over the span of the study, the authors wrote: "While folic acid deficiency is common in newly diagnosed CD, it is sometimes seen after diagnosis, perhaps because of a lack of folic acid in the gluten-free diet.
Previous studies have shown that folic acid deficiency in pregnancy leading to birth defects like cleft lip and palate (CPL) and anencephaly - one of the most common neural tube defects (NTD) in which a baby is born without the major portion of brain, skull and scalp - in children.