fetal hemoglobin

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Related to Foetal haemoglobin: Hb F, Haemoglobin F

he·mo·glo·bin F

[MIM*142200]
normal fetal Hb (Hb F) of molecular formula α2Aγ2F, which is the major Hb component during intrauterine life, decreasing rapidly during infancy to reach a concentration of less than 0.5% in normal children and adults; the concentration of Hb F is increased in some hemoglobinopathies and in some cases of hypoplastic anemia, pernicious anemia, and leukemia; Hb F has a weaker affinity for 2,3-bisphosphoglycerate than does Hb A. More than 50 mutant variants of the γ chain have been reported.
Synonym(s): fetal hemoglobin

fetal hemoglobin

n.
The predominant form of hemoglobin in fetuses and newborn infants, present in small amounts in adults but often elevated in adults with certain forms of anemia and other disorders.

fetal hemoglobin

hemoglobin F, the major hemoglobin present in the blood of a fetus and neonate. Hemoglobin F is present in only trace amounts in the blood of normal adults.

fetal hemoglobin

Hemoglobin F An immature Hb composed of 2 α and 2 γ chains that usually disappears in the neonatal period. See Hereditary persistence of fetal hemoglobin.
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