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flurbiprofen sodium

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flurbiprofen sodium,
the sodium salt of flurbiprofen, applied topically to the conjunctiva to inhibit miosis during, and as an antiinflammatory after, ophthalmic surgery.

flurbiprofen
(flrbip´rfen),
n brand name: Ansaid;
drug class: nonsteroidal antiinflammatory;
action: inhibits prostaglandin synthesis by interfering with cyclooxygenase needed for biosynthesis; possesses analgesic, antiinflammatory, antipyretic properties;
uses: acute, long-term treatment of rheumatoid arthritis, osteoarthritis.
flurbiprofen sodium,
n brand name: Ocufen;
drug class: nonsteroidal antiinflammatory ophthalmic;
action: inhibits enzyme system necessary for biosynthesis of prostaglandins, inhibits miosis;
uses: inhibition of intraoperative miosis, corneal edema.

antiinflammatory drug 
A drug which inhibits or suppresses most inflammatory responses of an allergic, bacterial, traumatic or anaphylactic origin, as well as being immunosuppressant. They include the corticosteroids (e.g. betamethasone, dexamethasone, fluorometholone, hydrocortisone acetate, loteprednol etabonate, prednisolone, rimexolone, triamcinolone). They are sometimes combined with an antibiotic drug (e.g. betamethasone combined with neomycin or sulfacetamide, dexamethasone combined with neomycin or polymyxin B). Corticosteroids have side effects, such as enhancing the activity of herpes simplex virus, fungal overgrowth, raising intraocular pressure or cataract formation.There are other antiinflammatory drugs that are non-steroidal (NSAID) and have little toxicity. They act mainly by blocking prostaglandin synthesis. These include diclofenac sodium, flurbiprofen sodium, indomethacin, ketorolac, nepafenac and oxyphenbutazone. See immunosuppressants; steroid.


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