Health-promoting Effects of the Citrus Flavanone
down arrow] Neointima proliferation (2008) [down arrow] free radical formation [down arrow] LOX-1 expression DPPH, l,l-diphenyl-2-picrylhydrazyl; LOX-1, lectin-like oxyLDL receptor-1; ACAT2, acyl CoA: cholesterol O-acyltransferase; MTP, microsomal triglyceride transfer pro-tein; VLDL-C, very low density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; HDL-C, high density lipoprotein cholesterol; HMG-CoA, 3-hydroxy-3- methylglutaryl-Co-enzyme A; HMGR, 3-hydroxy-3-methyl-glutaryl flavanones
Assessment of the effects of naringenin-type flavanones
in uterus and vagina.
The transcriptome analysis of five flavonoid biosynthesis related structural genes encoding chalcone isomerase (GhCHI) flavanone
3-hydroxylase (GhF3H) dihydroflavonol 4-reductase (GhDFR) anthocyanidin synthase (GhANS) and anthocyanidin reductase (GhANR) was performed at two fiber developmental stages i.
Considering the only structural differences between hesperidin and hesperetin naringin and naringenin were the free 7-OH group replaced by 7-O--Glc (61)--Rha and 7-O-- Glc(21)--Rha the presence of free 7-OH enhances the antiplatelet activities of flavanones
The study, of more than 69,000 women, attributed the preventive health benefits of citrus to a subgroup of flavonoids called flavanones
, which are found in citrus juices.
Compounds covered include flavanones
, flavonols, flavones, isoflavones, dihydrochalcones, resveratrol, and ellagic acid.
Tsuchiya H, Sato M, Miyazaki T, Fujiwara S, Tanigaki S, Ohyama M, Tanaka T, Iinuma M (1996) Comparative study on the antibacterial activity of phytochemical flavanones
against methicillin-resistant Staphylococcus aureus.
Researchers examined the relationship of the six main subclasses of flavonoids commonly consumed in the US diet - flavanones
, anthocyanins, flavan-3-ols, flavonoid polymers, flavonols and flavones - with risk of ischemic, hemorrhagic and total stroke.
Fruits contain a wide range of phytochemicals, ranging from anthocyanins and resveratrol in dark-colored grapes, quercetin in apples, to flavanones
such as hesperidin and naringin in citrus.
However, women who ate high amounts of flavanones
in citrus fruits had a 19 percent lower risk of blood clotrelated (ischemic) stroke than women who consumed the least amounts.
With a complex chemical composition, the main components are essential oils, phenols, polyphenols, flavanones
, chalcones, and prenyilates derived from p-coumaric acid (Ghisalberti, 1979; Bonvehi et al.