azelaic acid

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Related to Finacea: Azelaic acid, rosacea

azelaic acid

 [az″ĕ-la´ik]
a dicarboxylic acid occurring in whole grains and animal products; it has antibacterial effects on both aerobic and anaerobic organisms, particularly Propionibacterium acnes and Staphylococcus epidermidis, normalizes keratinization, and has a cytotoxic effect on malignant or hyperactive melanocytes; applied topically in the treatment of acne vulgaris.

azelaic acid

/az·e·la·ic ac·id/ (az″ĕ-la´ik) a topical antibacterial used in the treatment of acne vulgaris.

azelaic acid

[az′ĕ-la′ik]
a dicarboxylic acid occurring in whole grains and animal products. It has antibacterial effects on both aerobic and anaerobic organisms, particularly Propionibacterium acnes and Staphylococcus epidermidis; normalizes keratinization; and has a cytotoxic effect on malignant or hyperactive melanocytes. It is applied topically in the treatment of acne vulgaris.

azelaic acid

A substance first identified in rancid oleic acid which interferes with anerobic glycolysis and mitochondrial activity. Azelaic acid has antimicrobial activity against Propionibacterium acnes and Staphylococcus epidermidis, possibly by inhibiting microbial protein synthesis.

Dermatology
AZELEX Cream is indicated for the topical treatment of mild to moderate inflammatory acne vulgaris; another formulation, Finacea, is a topical gel used to manage inflammatory papules and pustules of mild to moderate rosacea.

Fringe oncology
Some anecdotal data suggest possible efficacy of alelaic acid in managing lentigo maligna, a form of melanoma.

azelaic acid

An antibacterial drug used externally in the form of a skin cream. A brand name is Skinoren.

azelaic acid (az´əla´ik),

n brand name: Azelex;
drug class: a naturally occurring straight-chain dicarboxylic acid;
action: has antimicrobial activity against
P. acnes and
S. epidermidis; use: topical therapy of mild-tomoderate inflammatory acne vulgaris.
References in periodicals archive ?
The two treatments showed equal efficacy in terms of reductions in inflammatory lesions, erythema, and physicians' global severity scores; however, only 26% of patients in the MetroGel group indicated they were bothered by stinging and burning, compared with 47% on Finacea.
Patients Bothered by Treatment-Related Stinging and Burning MetroGel 26% Finacea 47% Note: Based on a study of 180 patients.
Please see full Prescribing Information for FINACEA at www.
Finacea (rhymes with rosacea) is expected to be available early this year.
In addition to the website, Glow Worm developed a new Finacea consumer brand strategy, an integrated CRM email newsletter campaign, a patient starter packet and a printed brochure.
For patients who have been prescribed FINACEA for their mild to moderate papulopustular rosacea, or for those who seek more information about the drug, a special section covers the therapy in detail, including how to properly apply the gel, what to expect from the treatment and when to expect results, as well as actual patient photos showing clinical outcomes.
Stringfellow oversaw the introductions of six significant products for Berlex during his tenure: Mirena, Finevan, Yasmin, Refludan, Campath and Finacea.
In the latter, she directed the company's entry into the market, creating marketing, sales and clinical development competencies within the company and launching such products as Finacea.