filaggrin

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fil·ag·grin

(fil-ag'grin), [MIM*135940]
A major protein of the keratohyalin granule, composed mostly of l-histidyl, l-lysyl, and l-arginyl residues (stratum corneum basic proteins). It aggregates keratin intermediate filaments and promotes disulfide bond formation.
[filament + aggregating]

filaggrin

an intermediate filament-associated protein which is involved in cross-linking of keratin; the main constituent of keratohyalin in the granular layer of the epidermis.
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