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Fibrosis

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson 0.01 sec.
fibrosis /fi·bro·sis/ (fi-bro´sis) formation of fibrous tissue.fibrot´ic
congenital hepatic fibrosis  a developmental disorder of the liver marked by formation of irregular broad bands of fibrous tissue containing multiple cysts formed by disordered terminal bile ducts, resulting in vascular constriction and portal hypertension.
cystic fibrosis , cystic fibrosis of the pancreas a generalized hereditary disorder of infants, children, and young adults, with widespread dysfunction of exocrine glands, signs of chronic pulmonary disease, obstruction of pancreatic ducts by eosinophilic concretions and consequent pancreatic enzyme deficiency, and other symptoms.
endomyocardial fibrosis  idiopathic myocardiopathy seen endemically in parts of Africa and less often in other areas, characterized by cardiomegaly, thickening of the endocardium with dense, white fibrous tissue that often extends to involve the inner third or half of the myocardium, and congestive heart failure.
idiopathic pulmonary fibrosis  chronic inflammation and progessive fibrosis of the pulmonary alveolar walls, with progressive dyspnea and potentially fatal lack of oxygen or right heart failure. The acute form is called Hamman-Rich syndrome.
mediastinal fibrosis  fibrous mediastinitis; development of white, hard fibrous tissue in the upper portion of the mediastinum, sometimes obstructing the air passages and large blood vessels.
nodular subepidermal fibrosis 
2. a type of benign fibrous histiocytoma marked by subepidermal formation of fibrous nodules as a result of productive inflammation.
pleural fibrosis  fibrosis of the visceral pleura so that part or all of a lung becomes covered with a thick layer of nonexpansible fibrous tissue; fibrothorax is a more extensive form.

fi·bro·sis (f-brss)
n.
The formation of fibrous tissue as a reparative or reactive process.

fi·brotic (-brtk) adj.

Fibrosis
Formation of fibrous tissue as a reaction or as a repair process; may occur due to treatment and/or disease. in lymphedema condition known as hardening of the limb with resulting restriction of circulatory flow, increased infection, and weeping sores.

fibrosis (fībrō´sis),
n 1. the process of forming fibrous tissue, usually by degeneration (e.g., fibrosis of the pulp). The process occurs normally in the formation of scar tissue to replace normal tissue lost through injury or infection.
2. an abnormal condition in which fibrous connective tissue spreads over or replaces normal smooth muscle or other normal organ tissue. Fibrosis is most common in the heart, lung, peritoneum, and kidney.
fibrosis, diffuse hereditary gingival,
n an uncommon form of severe gingival hyperplasia considered to be of genetic origin. The tissue is pink, firm, dense, and insensitive and has little tendency to bleed.
fibrosis, hereditary gingival,
n an uncommon form of severe gingival hyperplasia that may begin with the eruption of the deciduous or permanent teeth and is characterized by a firm, dense, pink gingival tissue with little tendency toward bleeding.

fibrosis
formation of fibrous tissue; fibroid degeneration.

postfibrinous fibrosis
that occurring in tissues in which fibrin has been previously deposited.
proliferative fibrosis
that in which the fibrous elements continue to proliferate after the original causative factor has ceased to operate.

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Pharmaxis chief executive officer Dr Alan Robertson said: "The FDA decision is encouraging news for thousands of cystic fibrosis patients.
Tokyo, Japan, Dec 26, 2006 - (JCN) - Shionogi announced on December 22 that it has achieved the primary objectives of Phase III clinical trials for the idiopathic pulmonary fibrosis treatment S-7701, generic name pirfenidone, which the Company is developing in Japan under a license from U.
A defective gene in the bodies of cystic fibrosis patients causes the body to produce abnormally thick, sticky mucus that clogs the lungs and leads to life-threatening infections.
 
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