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fibrocystic disease

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fibrocystic disease,
fibrocystic disease
Chronic cystic mastitis, fibrocystic disease Surgical pathology A common benign disease of the ♀ breast, first seen circa age 40, which presents as diffuse rubbery induration, punctuated by dilated ducts and variably-sized cysts Major patterns Cysts plus fibrosis; sclerosing adenosis; epithelial hyperplasia, which ↑ CA risk. See Ductal intraepithelial neoplasia.
fibrocystic disease
No risk for future cancer: FCD with adenosis–sclerosing or florid, apocrine metaplasia, cysts–macro- or microscopic, ductal ectasia, fibroadenoma, fibrosis, hyperplasia
Minimal risk for future cancer: with glandular 'crowding', ie 2-4 epithelial cells in depth, mastitis, especially periductal, squamous metaplasia
1.5-2-foldrisk of future cancer: with hyperplasia–moderate or florid, solid or papillary or in a papilloma with a fibrovascular core
2-5-foldrisk of future cancer: with atypical hyperplasia–borderline lesion, either ductal or lobular
8-10-fold ≠ risk of future invasive cancer Carcinoma-in-situ


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Fibrocystic disease is common in more than half of all women, and is more noticeable during the time around your menstrual cycle, as this is influenced by hormone levels.
Nomenclature contributes to the problem, with various terms such as mastodynia, mastitis and fibrocystic disease being used.
The close relationship between iodine and healthy breasts free of fibrocystic disease and cancer might be interpreted to mean that all of us might do better with these greater intakes of iodine.
 
 
 
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