Fibroblasts


Also found in: Dictionary, Thesaurus, Encyclopedia.
Related to Fibroblasts: Chondroblasts, Myofibroblasts

Fibroblasts

A type of cell found in connective tissue; produces collagen.
Mentioned in: Skin Grafting
References in periodicals archive ?
They "reprogrammed" scar-forming fibroblast cells into the building blocks of beating heart muscle by injecting them with a cocktail of five genes.
The research team reprogrammed fibroblasts and established a laboratory-based system for producing hepatic stem cells.
Specifically, the researchers found that DNA-damaging cancer treatment coaxes fibroblasts to crank out a protein called WNT16B within the tumor neighborhood, or microenvironment, and that high levels of this protein enable cancer cells to grow, invade surrounding tissue, and resist chemotherapy.
In contrast, Derrick Rancourt's group at the University of Calgary used viral vectors to get ordinary mouse fibroblasts to express the Yamanaka factors.
Autologous cultured fibroblasts (20 million/ml) were given as two doses administered with two weeks interval.
11] During the progression of periodontal inflammation, periodontal ligament and gingival fibroblasts secrete high levels of cytokines and chemokines.
SpinalCyte is focused on regrowth of the spinal disc nucleus using human dermal fibroblasts.
Although the majority of the studies mainly compared the quantitative and morphological changes of collagen fibers and/or detected the impact of collagenase upon collagen metabolism, the pathogenesis of POP in terms of the variations in the synthesis and secretion of procollagen in fibroblasts have not been explored.
The proliferative capacity of fibroblasts was evaluated with the amount of DNA synthesis labeled with [sup.
The aim of the current study is to isolate homozygous [alpha]GT KO cells from postnatal heterozygous [alpha]GT KO skin fibroblasts and ultimately to evaluate the developmental competence of isolated homozygote cells after SCNT.
Statistically significant decreased expression of MUC1 gene after luteolin treatment of fibroblasts cells was also revealed.
Given the strong association between tissue injury, fibrosis, and calcification, the researchers hypothesized that maybe it is cardiac fibroblasts [cells that give rise to scar tissue after injury] that are contributing to the calcification process.

Full browser ?