Fibroblasts


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Related to Fibroblasts: Chondroblasts, Myofibroblasts

Fibroblasts

A type of cell found in connective tissue; produces collagen.
Mentioned in: Skin Grafting
References in periodicals archive ?
RA synovial fibroblasts were pretreated with SPE for 1 h, followed by stimulation with tumor necrosis factor (TNF)-[alpha] (10 ng/ml) for 12 h.
Cooke and his colleagues reported to Circulation that about 2 percent of the fibroblasts were transformed from fibroblasts into endothelial cells, a rate comparable to what other research groups have accomplished using viruses and gene therapy.
Most of the nuclei of the fibroblasts in the collagen bundles have disappeared making the graft acellular.
The number of fibroblasts in each group were compared using analysis of variance (ANOVA, [alpha]=0.
Inhibition of fibroblast activation protein and dipeptidylpeptidase 4 increases cartilage invasion by rheumatoid arthritis synovial fibroblasts.
If trials targeting fibroblasts work as well as they appear to be doing in the treatment of cancer, a whole new class of treatments distinct from current diseasemodifying medicines will become available, that will offer genuine alternative to existing drugs and offer the potential to help repair damaged joints.
Autologous cultured fibroblasts (20 million/ml) were given as two doses administered with two weeks interval.
Inspired by the discovery that fibroblasts could be reprogrammed with a combination of factors into cells that look and act a lot like embryonic stem cells, Deepak Srivastava and his colleagues at the University of California began working with 14 factors known to play a role in heart development.
Stem cells made from skin cells called fibroblasts in the tip of a mouse's tail aren't very good at becoming blood cells, for instance, says George Daley, a stem cell biologist at Children's Hospital Boston and Harvard University who coauthored the paper in Nature.
53BP1 foci were increased following gamma irradiation, consistent with expectations for cells requiring repair of radiation-induced DNA damage (23 and 32 foci/cell compared with approximately 1-2 or 2-4 foci/cell following sham exposure in fibroblasts and stem cells, respectively.
Analysis of fibroblasts is useful for several reasons (5), including confirmation of the defects observed in muscle, to exclude secondary mitochondrial dysfunction, e.
Bioengineers at Duke University in North Carolina, USA, also found the cells only flourished in the presence of other cells known as cardiac fibroblasts, which make up 60 per cent of cells in the human heart.

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