FGF14

(redirected from Fibroblast growth factor homologous factor 4)

FGF14

A gene on chromosome 13q34 that encodes fibroblast growth factor 14 of the FGF family, which bind heparin and have a broad range of cellular activities, including cell survival, division, differentiation and migration, embryonic development, morphogenesis, tissue repair, tumour growth and invasion. FGF14’s function is unknown; it is thought to play a role in nervous system development and function.

Molecular pathology
FXF14 mutations cause (autosomal dominant) spinocerebellar ataxia type 27.
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