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fibrates |
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fibrates /fi·brates/ (fi´brāts) general term for fibric acid (q.v.) derivatives. fibrates [fi′brāts] a general term for fibric acid derivatives, such as gemfibrozil. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Currently, a number of components of dyslipidemia are managed pharmacologically: statins to treat high cholesterol, fibrates for high triglycerides, and various medications to treat insulin resistance (a related metabolic disturbance). Activation of PPARs is the mechanism by which hypolipidemic fibrates induce hypolipidemia in humans (Clay et al. The combination of fibrates or nicotinic acid with statins has been identified as a potential risk factor (2); however, recent recommendations support consideration of this combination in patients at high risk for developing coronary events who have elevated triglycerides and low HDL-C. |
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