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fexofenadine

   Also found in: Acronyms, Wikipedia 0.28 sec.
fexofenadine /fex·o·fen·a·dine/ (fek″so-fen´ah-dēn) an antihistamine (H1-receptor antagonist) used as the hydrochloride salt in the treatment of hay fever and chronic idiopathic urticaria.
fexofenadine,
an antihistamine.
indications It is used to treat rhinitis and allergy symptoms.
contraindications Known hypersensitivity to this drug and severe hepatic disease prohibit its use. Its use is also contraindicated in lactating women and in newborn or premature infants.
adverse effects Life-threatening effects are hemolytic anemia, thrombocytopenia, leukopenia, agranulocytosis, pancytopenia, and arrhythmias (rare). Other adverse effects are urinary frequency, dysuria, urinary retention, impotence, thickening of bronchial secretions, dry nose and throat, nausea, diarrhea, abdominal pain, vomiting, constipation, headache, stimulation, drowsiness, sedation, fatigue, confusion, blurred vision, tinnitus, restlessness, tremors, paradoxical excitation in children or the elderly, rash, eczema, photosensitivity, urticaria, hypotension, palpitations, bradycardia, and tachycardia.


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Newer, non-sedating antihistamines like fexofenadine (Allegra) and Ioratadine (Claritin) don't appear to be as effective.
Her medical history was significant for perennial allergic rhinitis and gastroesophageal reflux disease, for which she took fexofenadine and rabeprazole, respectively.
In July, the FDA approved Allegra, known generically as fexofenadine.
 
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