More research produced the answer: Vitamin C induced what is known as a Fenton reaction
, causing iron to react with other molecules to create reactive oxygen species that kill the TB bacteria.
The paper is titled, "Mycobacterium tuberculosis is extraordinarily sensitive to killing by a vitamin C-induced Fenton reaction
After further research, the team found vitamin C kills the virus by inducing what is known as a Fenton reaction
21-22) Specifically, the Fenton reaction
involves transition metal cations, usually ferric or cupric ions, being reduced to ferrous or cuprous ions by a reducing agent such as vitamin C.
dGlyage showed in vitro its ability to interact with Cu2+, preventing DNA damage caused by the OH generated by Fenton reaction
It was concluded that rutin and quercetin are able to suppress free radical processes at three stages: the formation of superoxide ion, the generation of hydroxyl (or cryptohydroxyl) radicals in the Fenton reaction
and the formation of lipid peroxy radicals.
It also adds a section on non-specific methods for the destruction of hazardous organic chemicals, including potassium permanganate oxidation and advanced oxidation processes, such as the Fenton reaction
Alternatively, hydroxyl radicals can be generated through the Fenton reaction
formed by the oxidation of ferrous salts in the presence of hydrogen peroxide.
The scavenging activity for hydroxyl radicals was measured with Fenton reaction
(Sadasivam and Manikam, 1992).
The Fenton reaction
was also carried out at pH = 3.
On the other hand, the Fenton reaction
depends on the type of zeolite, suggesting that the surface structure of the iron on the zeolite plays an important role (Fach et al.
The CMFR system is designed to simulate the chemistry employed by brown-rot fungi in producing a "sustained" Fenton reaction
to degrade and/or modify wood.