Fen-Phen

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fen-phen

(fĕn′fĕn′)
n.
A combination of two drugs, fenfluramine hydrochloride and phentermine, formerly prescribed for weight loss but withdrawn from the market in 1997 because of potentially dangerous side effects.

Fen-Phen

Cardiology A once-popular combination of 2 anorectic agents, fenfluramine and phentermine; the theoretical advantage of using 2 different agents is that the dose of each agent could be lowered Adverse effects The fen-phen combination is associated with valvular heart disease and fatal pulmonary HTN; it was withdrawn from the market. See Fenfluramine.

Fen-Phen

(fen´-fen´),
n a combination of fenfluramine hydrochloride and phentermine hydrochloride, two stimulants, which promotes weight loss by reducing appetite. It is no longer available due to its damaging of the heart's valves. Thus it is important for a patient who has a history of using this medication to get a cardiac screening to check for risk of bacterial endocarditis. See also fenfluramine hydrochloride and phentermine hydrochloride.