fen-phen (f n fn)n. A combination of the drugs fenfluramine and phentermine, formerly prescribed for weight loss, whose use was discontinued because of association with pulmonary hypertension. |
Fen-Phen
(fen´-fen´),
n a combination of fenfluramine hydrochloride and phentermine hydrochloride, two stimulants, which promotes weight loss by reducing appetite. It is no longer available due to its damaging of the heart's valves. Thus it is important for a patient who has a history of using this medication to get a cardiac screening to check for risk of bacterial endocarditis. See also fenfluramine hydrochloride and phentermine hydrochloride.
n a combination of fenfluramine hydrochloride and phentermine hydrochloride, two stimulants, which promotes weight loss by reducing appetite. It is no longer available due to its damaging of the heart's valves. Thus it is important for a patient who has a history of using this medication to get a cardiac screening to check for risk of bacterial endocarditis. See also fenfluramine hydrochloride and phentermine hydrochloride.
Fen-Phen
Cardiology A once-popular combination of 2 anorectic agents, fenfluramine and phentermine; the theoretical advantage of using 2 different agents is that the dose of each agent could be lowered Adverse effects The fen-phen combination
is associated with valvular heart disease and fatal pulmonary HTN; it was withdrawn from the market. See Fenfluramine.
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