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Femara |
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letrozole Warning - Hazardous drug! Femara Pharmacologic class: Aromatase inhibitor Therapeutic class: Antineoplastic Pregnancy risk category D ActionInhibits aromatase, an enzyme that promotes conversion of estrogen precursors to estrogen. This inhibition reduces circulating estrogen levels and stops progression of breast cancer. AvailabilityTablets: 2.5 mg ⊘Indications and dosages ➣ Metastatic or advanced breast cancer in postmenopausal women; early breast cancer in postmenopausal women who have received 5 years of antiestrogen therapy Adults: 2.5 mg P.O. daily Contraindications• Hypersensitivity to drug or its components PrecautionsUse cautiously in: Administration• Give with or without meals.
Adverse reactionsCNS: anxiety, depression, dizziness, drowsiness, fatigue, headache, vertigo, asthenia CV: chest pain, hypertension GI: nausea, vomiting, diarrhea, constipation, abdominal pain, dyspepsia, anorexia Metabolic: hypercalcemia Musculoskeletal: musculoskeletal or joint pain, fractures Respiratory: cough, dyspnea, pleural effusion Skin: alopecia, pruritus, rash, diaphoresis Other: hot flashes, edema, weight gain InteractionsDrug-diagnostic tests. Cholesterol, gamma-glutamyltransferase: increased levels Patient monitoring• Check vital signs and assess cardiovascular and respiratory status. Patient teaching• Tell patient she can take with or without food. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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