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a syndrome of splenomegaly with chronic rheumatoid arthritis and leukopenia; there are usually pigmented spots on the skin of the lower extremities, and sometimes there is other evidence of hypersplenism such as anemia or thrombocytopenia.
Etymology: Augustus R. Felty, American physician, 1895-1963
a group of pathological changes that occurs with adult rheumatoid arthritis, characterized by splenomegaly, leukopenia, frequent infections, and sometimes thrombocytopenia and anemia. The cause of the syndrome is unknown. Surgical resection of the spleen offers temporary improvement in about one half of the cases. See also hypersplenism.
Felty's syndromeRHEUMATOID ARTHRITIS associated with enlargement of the SPLEEN and a reduction in the number of white cells in the blood. There is also often anaemia, loss of weight, enlarged lymph nodes and an increased susceptibility to infection. (Augustus Roi Felty, 1885–1963, American physician).
An autoimmune disorder in which neutropenia is associated with rheumatoid arthritis and an enlarged spleen.
Mentioned in: Neutropenia