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felodipine |
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felodipine /fe·lo·di·pine/ (fe-lo´di-pen) a calcium channel blocker used as a vasodilator in the treatment of hypertension. felodipine (f  lō´dpēn´), n brand names: Plendil, Renedil; drug class: calcium channel blocker; action: inhibits calcium ion influx across cell membrane during cardiac depolarization; produces relaxation of coronary vascular smooth muscle; dilates coronary arteries; decreases SA/AV node conduction; uses: essential hypertension, alone or with other antihypertensives, chronic angina pectoris. |
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| Over the next 24 hours, the researchers monitored felodipine concentrations in each volunteer's blood. Although not marketed in the United States, nitrendipine is a member of the dihydropyridine calcium channel blocker class, which includes amlodipine, nifedipine and felodipine. When they gave grapefruit juice to their volunteers to mask the taste of the alcohol, the researchers found four times the expected amount of felodipine in their blood (SN: 2/9/91, p. |
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felodipine
