Fc fragment

(redirected from Fc piece)

Fc frag·ment

the crystallizable fragment of an immunoglobulin molecule composed of the constant regions of the heavy chains and responsible for binding to antibody receptors (Fc receptor) on cells and the Clq component of complement.
Synonym(s): Fc piece

Fc frag·ment

, Fc (frag'mĕnt)
The crystallizable fragment of an immunoglobulin molecule composed of part of the heavy chains and responsible for binding to antibody receptors on cells and the Clq component of complement.

Fc fragment

A small piece of an immunoglobulin (an antibody) used by macrophages in processing and presenting foreign antigens to T lymphocytes.
See: immune response; macrophage processing

Fc fragment

a portion of an immunoglobulin molecule, produced by papain digestion, with parts of two heavy chains. It has no antigen-combining sites, but contributes to a number of effector functions such as the binding of antibody to Fc receptors on a variety of cells, the transfer of antibody from the circulation into colostrum, the transfer across the gut of the newborn, and the binding of complement.