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Fc fragment |
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Fc fragment a portion of an immunoglobulin molecule, produced by papain digestion, with parts of two heavy chains. It has no antigen-combining sites, but contributes to a number of effector functions such as the binding of antibody to Fc receptors on a variety of cells, the transfer of antibody from the circulation into colostrum, the transfer across the gut of the newborn, and the binding of complement. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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The arms perform the work of venom neutralization, while the bottom leg, known as the Fc fragment, triggers the unwanted immune reactions in people. Virdante also announced today that the Company plans to use the proceeds from the new financing to pursue development of a second drug, a sialylated recombinant IgG Fc fragment ("sFc"), the segment of IgG responsible for the anti-inflammatory activity of IVIG. In intact antibodies, that amino acid portion -- called the Fc fragment -- normally mediates two powerful immune responses: It helps killer white blood cells recognize and ingest antibody-bound foreign invaders and it triggers a process known as complement activation that destroys those invaders by chemical dissolution. |
Fc fragment |
FBWG FBWI FBWK FBWL FBWM FBWMA FBWP FBWR FBWSC FBWT FBWW FBX FBX-T FBY FBYC FBYM FBYV FBZ fc fc fc fc FC Baur FC connector FC CPTR FC Dallas FC DASA Fc fragment Fc Fragment of Igg, Low Affinity IIa, Receptor forFc gamma receptor III Fc immunoglobulin Fc immunoglobulin Fc immunoglobulin FC Metalist Kharkiv Fc r Fc r Fc r Fc r FC Real Bristol Fc receptor Fc receptor Fc receptor Fc receptor Fc region FC Wacker Innsbruck FC&CE FC&G FC&S FC-43 FC-AFC Fc-al Fc-al FC-BGA FC-BSA FC-FBF FC-FED FC-GS FC-MI | ||||||||
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