Fc


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Fc frag·ment

the crystallizable fragment of an immunoglobulin molecule composed of the constant regions of the heavy chains and responsible for binding to antibody receptors (Fc receptor) on cells and the Clq component of complement.
Synonym(s): Fc piece

Fc

fragment, crystallizable; a fragment by papain digestion of immunoglobulin molecules. It contains most of the antigenic determinants.

Fc

a part of a molecule of an antibody that has been split by a proteolytic enzyme. It represents the relatively constant region, as distinguished from the Fab portion, that contains the binding sites. The Fc portion is sometimes identified as the crystallizable fragment.

Fc frag·ment

, Fc (frag'mĕnt)
The crystallizable fragment of an immunoglobulin molecule composed of part of the heavy chains and responsible for binding to antibody receptors on cells and the Clq component of complement.

Fc

A crystallizable, non-antigen-binding fragment of an antibody molecule obtained by brief digestion with the enzyme papain. It consists of the C-terminal part of both heavy chains, the part which binds to FC RECEPTORS.