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Necrosis |
Also found in: Wikipedia, Hutchinson | 0.04 sec. |
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necrosis /ne·cro·sis/ (ne-kro´sis) pl. necro´ses [Gr.] the morphological changes indicative of cell death caused by progressive enzymatic degradation; it may affect groups of cells or part of a structure or an organ. aseptic necrosis necrosis without infection, usually in the head of the femur after traumatic hip dislocation. Balser's fatty necrosis gangrenous pancreatitis with omental bursitis and disseminated patches of necrosis of fatty tissues. caseous necrosis cheesy n. central necrosis that affecting the central portion of an affected bone, cell, or lobule of the liver. cheesy necrosis that in which the tissue is soft, dry, and cottage cheese–like; most often seen in tuberculosis and syphilis. coagulation necrosis necrosis of a portion of some organ or tissue, with formation of fibrous infarcts, the protoplasm of the cells becoming fixed and opaque by coagulation of the protein elements, the cellular outline persisting for a long time. colliquative necrosis that in which the necrotic material becomes softened and liquefied. contraction band necrosis a cardiac lesion characterized by hypercontracted myofibrils and contraction bands and mitochondrial damage, caused by calcium influx into dying cells resulting in arrest of the cells in the contracted state. fat necrosis that in which the neutral fats in adipose tissue are split into fatty acids and glycerol, usually affecting the pancreas and peripancreatic fat in acute hemorrhagic pancreatitis. liquefaction necrosis colliquative n. phosphorus necrosis necrosis of the jaw bone due to exposure to phosphorus. postpartum pituitary necrosis necrosis of the pituitary during the postpartum period, often associated with shock and excessive uterine bleeding during delivery, and leading to variable patterns of hypopituitarism. subcutaneous fat necrosis induration of the subcutaneous fat in newborn and young infants. necrosis ustilagi´nea dry gangrene due to ergotism. Zenker's necrosis see under degeneration.
Necrosis The death of cells, a portion of tissue, or a portion of an organ due to permanent damage of some sort, such as a lack of oxygen supply to the tissues. necrosis (n n tissue death due to disease or localized injury. necrosis (nekrō´sis), n 1. the death of a cell or group of cells in contact with living tissue. n 2. the local death of cells resulting from, e.g., loss of blood supply, bacterial toxins, or physical or chemical agents. necrosis, avascular n the consequence of temporary or permanent cessation of blood flow to the bones. The absence of blood causes the bone tissue to die, resulting in fracture or collapse of the entire bone. necrosis, caseous n a change commonly associated with tuberculosis and characterized by dry, soft, and cheesy tissue. necrosis, exanthematous n an acute necrotizing process involving the gingivae, jawbones, and contiguous soft tissues. It is of unknown cause, primarily affects children, and resembles noma. It differs from noma, however, in that it has a slight odor, tendency for self-limitation, low mortality rate, and normal leukocyte count. See also noma. necrosis, gingival, n death and degeneration of the cells and other structural elements of the gingivae (e.g., necrotizing ulcerative gingivitis). necrosis, interdental, n a progressive disease that destroys the tissue of the papillae and creates interdental craters. Advanced interdental necrosis leads to a loss of periodontal attachment. necrosis, ischemic, n death and disintegration of a tissue resulting from interference with its blood supply, thus depriving the tissues of access to substances necessary for metabolic sustenance. It may occur in the periodontal ligament as a result of occlusal trauma. necrosis of epithelial attachment, n the death of cells composing the epithelial attachment. In a specific periodontitis produced by organisms similar to Actinomyces, necrosis of the epithelial attachment may exist, permitting a rapid apical shift of the base of the pocket. necrosis, periodontal ligament, n necrosis of a portion of the periodontal ligament, usually resulting from traumatic injury (e.g., in occlusal traumatism). Much of this necrotic change is the result of ischemia. necrosis, radiation, n the death of tissue caused by radiation. necrosis pl. necroses [Gr.] the morphological changes indicative of cell death caused by enzymatic degradation. aseptic necrosis necrosis without infection or inflammation. caseous necrosis necrosis in which the tissue is soft, dry and cheesy, occurring typically in tuberculosis. central necrosis necrosis affecting the central portion of an affected bone, cell or lobule of the liver. cheesy necrosis that in which the tissue resembles cottage cheese; most often seen in tuberculosis. coagulation necrosis death of cells, the protoplasm of the cells becoming fixed and opaque by coagulation of the protein elements, the cellular outline persisting for a long time. colliquative necrosis see liquefactive necrosis (below). liquefactive necrosis necrosis in which the necrotic material becomes softened and liquefied. moist necrosis necrosis in which the dead tissue is wet and soft. Zenker's necrosis hyaline degeneration and necrosis of striated muscle; called also Zenker's degeneration. |
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