ALDH3A2

(redirected from Fatty aldehyde dehydrogenase)

ALDH3A2

A gene on chromosome 17p11.2 that encodes an aldehyde dehydrogenase that plays a major role in detoxifying aldehydes generated by alcohol metabolism and lipid peroxidation. The ALDH3A2 gene product catalyses the oxidation of long-chain aliphatic aldehydes to fatty acid.

Molecular pathology
ALDH3A2 mutation causes Sjögren-Larsson syndrome.
References in periodicals archive ?
Studies by Rizzo and coworkers (3-5) have identified the enzyme that is deficient in SLS as fatty aldehyde dehydrogenase (FALDH; EC 1.
Deficient activity of the fatty aldehyde dehydrogenase component of fatty alcohol:[NAD.
The molecular basis of Sjogren-Larsson syndrome: mutation analysis of the fatty aldehyde dehydrogenase gene.
It is caused by mutations in a gene called ALDH3A2, a gene that provides instructions for making an enzyme called fatty aldehyde dehydrogenase (FALDH).