ampakine

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ampakine

An AMPA-type glutamine receptor agonist (e.g., CX516) which facilitates synaptic transmission by binding to glutamate and enhancing long-term potentiation, a critical component in memory. Amakines enhance the activity of AMPA receptor-rich neurons by amplifying neural signals, and are reported to improve memory in early trials in Alzheimer’s disease and schizophrenia.

ampakine

Neuropharmacology Any compound that facilitates synaptic transmission by binding to glutamate and enhance long-term potentiation, a critical component in long term memory, by enhancing the activity of AMPA receptor-rich neurons which enhance AMPA receptor activity by amplifying neural signals generated by glutamate binding; ampakines improve memory in early trials in Alzheimer's disease, schizophrenia See AMPA receptor, Long-term potentiation.
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