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Fansidar

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Sulfadoxone/pyrimethamine (Fansidar)
An antimalarial drug developed in the 1960s. It is the first drug tried in some parts of the world where chloroquine resistance is widespread. It has been associated with severe allergic reactions due to its sulfa component.
Mentioned in: Malaria

Fansidar,
trademark for a fixed-combination antimalarial agent (pyrimethamine and sulfadoxine).


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Although the parasite has grown resistant to drugs that once tamed the disease--including the Fansidar distributed in the Ndirande clinic--it's easily treatable with a powerful drug called artemisinin.
The mutation may have favored acquisition of type 1 rather than another type by the three patients who were receiving suboptimal prophylaxis with Fansidar (Roche, Nutley, NJ).
Other drugs to note are Artesunate, Fansidar (sulfadoxine/pyrimethamine), and chloroquine/proguanil, because they sometimes will be taken by travelers who have symptoms while still overseas.
 
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