long QT syndrome

(redirected from Familial long QT syndrome)
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long QT syndrome

 
a combination of prolonged Q–T interval and torsades de pointes; it may be congenital or acquired, the latter usually being the result of drug administration.

long QT syndrome

an inherited cardiac disorder characterized by prolongation of the Q-T interval. The disorder is associated with ventricular tachycardia, cardiac arrhythmias, syncope, and sudden death. Syncopal episodes often occur during physical exercise in young, otherwise healthy persons. This syndrome may also be caused by a variety of drugs.

prolonged QT syndrome

, long QT syndrome, QT syndrome
A life-threatening syndrome marked by a prolonged Q-T interval with episodes of electrocardiographic torsades de pointes. This condition may be inherited or may be acquired as a result of drug administration. Inherited variants of the long QT syndrome include Romano-Ward syndrome and Lange-Nielsen syndrome. It is treated with beta-blocking drugs or an implanted cardioverter defibrillator (ICD).
References in periodicals archive ?
The revised warnings say that although cases of sudden death, TdP, and QT prolongation have been reported in patients with no predisposing factors, "particular caution" is recommended in using any formulation of haloperidol in patients who have other QT-prolonging conditions, including electrolyte imbalance (particularly hypokalemia and hypomagnesemia), underlying cardiac abnormalities, hypothyroidism or familial long QT syndrome, or who are taking drugs known to prolong the QT interval.
The FAMILION test is indicated for individuals with suspected Familial Long QT Syndrome, Brugada Syndrome, Short QT Syndrome, or related syndromes, or for family members of individuals who have previously tested positive for a genetic variant associated with one of these conditions.
The Company's FAMILION([R]) test, launched in 2004, is intended for individuals with suspected Familial Long QT Syndrome, Brugada Syndrome, Short QT Syndrome, or related syndromes, or for family members of individuals who have previously tested positive for a genetic variant associated with one of these conditions.
The proprietary FAMILION test is intended for individuals with suspected Familial Long QT Syndrome, Brugada Syndrome, Short QT Syndrome, or related syndromes, or for family members of individuals who have previously tested positive for a genetic variant associated with one of these conditions.
The division is also responsible for the development of a safety biomarker for use with the anti-psychotic clozapine and of genetic markers for cardiac channelopathies including Familial Long QT Syndrome (LQTS), Brugada Syndrome, Short QT Syndrome (STQS), and related syndromes.

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