familial hemophagocytic lymphohistiocytosis

(redirected from Familial Erythrophagocytic Lymphohistiocytosis)
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familial hemophagocytic lymphohistiocytosis (FMLH),

an extremely rare, usually fatal disease of childhood characterized by multiorgan infiltration by activated macrophages and lymphocytes. The disease is often familial and appears to be inherited as an autosomal recessive trait.

familial hemophagocytic lymphohistiocytosis

Etymology: L, familia, household; Gk, histion, web, kytos, cell; L, reticulum, little net; Gk, osis, condition
an autosomal-recessive disease, characterized by anemia, granulocytopenia, and thrombocytopenia. Phagocytosis of blood cells and infiltration of bone marrow by macrophages commonly cause death in childhood. Also called familial hemophagocytic reticulosis.

fa·mil·i·al he·mo·pha·go·cyt·ic lymph·o·his·ti·o·cy·to·sis

(FMLH) (fă-mil'ē-ăl hē'mō-fāg'ō-sit'ik lim'fō-his'tē-ō-sī-tō'sis)
An extremely rare, usually fatal disease of childhood characterized by multiorgan infiltration with activated macrophages and lymphocytes. The disease is often familial and appears to be inherited as an autosomal recessive trait.
Synonym(s): familial erythrophagocytic lymphohistiocytosis.
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