They found that patients whose microbiomes were diverse in general, and in particular were enriched with Faecalibacterium
and Clostridiales species, were more likely to respond to immunotherapy with a PD-1 inhibitor and have a longer duration of progression-free survival.
Effect of inulin on the human gut microbiota: stimulation of Bifidobacterium adolescentis and Faecalibacterium
As an internal control for qPCR experiments, the following bacterial ATCC (American type culture collection) standard strains were used: Akkermansia muciniphila ATCC BAA-835, Faecalibacterium
prausnitzii ATCC 27766, Bifidobacterium breve ATCC 15700, Lactobacillus acidophilus ATCC 4356, Bacteroides fragilis ATCC 25285, Escherichia coli ATCC 25922.
Enhanced butyrate formation by cross-feeding between Faecalibacterium
prausnitzii and Bifidobacterium adolescentis.
Finlay and his colleagues identified a transient imbalance early in life in children with atopy, wheeze, and asthma of four specific bacterial taxa: Faecalibacterium
, Lachnospira, Veillonella, and Rothia.
The commensal bacterium Faecalibacterium
prausnitzii is protective in DNBS-induced chronic moderate and severe colitis models.
prausnitzii was the predominant species (Figure 3).
For example, Faecalibacterium
prausnitzii has recently been identified as an important gut bacterium that may be associated with Crohn's Disease.
The main dominant genera however changed after ginseng intake with Blautia, Bifidobacterium and Anaerostripes dominant prior to the intervention, whereas Bifidobacterium, Blautia and Faecalibacterium
were most abundant after intervention.
The diversity of the microbiota as well as the abundance of Faecalibacterium
prausnitzii (a prototype anti-inflammatory microbiota) has been shown significantly lower in obese patients and patients with type 2 diabetes compared with lean individuals .
We identified several decreased Firmicutes families following arsenic exposure, and a number of Firmicutes species, such as Eubacterium, Faecalibacterium
, and Roseburia, are known to be butyrate producers (Tremaroli and Backhed 2012).
As his metabolism improved, quantities of a bacterium called Faecalibacterium
prausnitzii increased in his gut.