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factor VII
(redirected from Factor VIIa)

   Also found in: Wikipedia 0.03 sec.
factor VII
n.
A factor in the clotting of blood that forms a complex with tissue thromboplastin and calcium to activate the prothrombinase, thus acting to accelerate the conversion of prothrombin to thrombin. Also called convertin, cothromboplastin, proconvertin, serum accelerator, serum accelerator globulin, serum prothrombin conversion accelerator.

factor VII A coagulation factor that forms a complex with thromboplastin and calcium to activate factor X


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Factor VIIa and thrombin induce the expression of Cyr61 and connective tissue growth factor, extracellular matrix signaling proteins that could act as possible downstream mediators in factor VIIa x tissue factor-induced signal transduction.
Relationships between homocysteine, factor VIIa, and thrombin generation in acute coronary syndromes.
Two of the new proteins thwart clotting by binding to and inactivating factor Xa; the third protein stymies factor VIIa and "inhibits the initiation of the entire coagulation cascade," says Vlasuk.
 
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