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factor V Leiden
(redirected from Factor V Leiden mutation)

   Also found in: Acronyms, Wikipedia 0.01 sec.
factor V Leiden
Hematology A variant of factor V present in 3%-8% of Caucasians associated with a ↑ risk of DVT. See LETS, Hereditary thrombophilia.


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The physicians found she had taken a relatively long car journey, of about an hour and a half, the day before; took a daily dose of oestrogen oral contraceptives; and had a genetic variant, called the factor V Leiden mutation, which is linked to a blood-clot disorder.
Verity DH, Vaughan R, Madanat W et al: Factor V leiden mutation is associated with ocular involvement in Behcet disease.
These protein deficiencies/abnormalities are genetic and include entities such as antithrombin deficiency, protein C deficiency, protein S deficiency, Factor V Leiden mutation, prothrombin 20210, and dysfibrinogenemia, among others.
 
 
 
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