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Fab

 (fragment, antigen-binding)
originally, either of two identical fragments, each containing an antigen combining site, obtained by papain cleavage of the IgG molecule; now generally used as an adjective in terms such as Fab fragment or region, referring to an “arm” of any immunoglobulin monomer, i.e., one light chain and the adjoining heavy chain VH and CH1 domains.
digoxin immune Fab (ovine) a preparation of antigen-binding fragments derived from specific antidigoxin antibodies produced in sheep that have been immunized with digoxin coupled as a hapten to human serum albumin, used as an antidote to life-threatening digoxin and digitoxin overdose; administered intravenously.

FAB

Abbreviation for French-American-British (classification of acute leukemias). See: FAB classification.

Fab

[f ragment, a ntigen-b inding] originally, either of two identical fragments, each containing an antigen combining site, obtained by papain cleavage of the immunoglobulin IgG molecule; now generally used as an adjective to refer to an “arm” of any immunoglobulin monomer.
digoxin immune Fab (ovine)  a preparation of antigen-binding fragments derived from specific antibodies produced against digoxin in sheep; used as an antidote to digoxin and digitoxin overdose.

Fab

the fragment of an antibody molecule that contains the antigen-binding site, consisting of a light chain and part of a heavy chain. Such fragments are produced when antibodies are digested by enzymes, such as the protease papain. Fab fragments are used as an antidote for treating toxicity caused by digoxin, digitoxin, and oleander tea. See also Fc, Digibind.

Fab

Etymology: fragment, antigen-binding
originally, either of two identical fragments, each containing an antigen combining site, obtained by papain cleavage of the IgG molecule. Now it is generally used as an adjective in terms such as Fab fragment or region, referring to an "arm" of any immunoglobulin monomer, i.e., one light chain and the adjoining heavy chain VH and CH1 domains.

alcopop

A popular term for any of the alternative beverages that were formulated in response to an increase in the US federal wine tax in the early 1990s. The spirits industry responded by moving away from wine coolers to malt-based alcoholic beverages including "hard" lemonades and fruit coolers and drinks.

FANCB

A gene on chromosome Xp22.2 that encodes a protein of the Fanconi anaemia complementation group (here, complementation group B), the members of which are related not by sequence similarity, but rather by their assembly into a common nuclear protein complex.

FAB

Abbreviation for French-American-British classification system.

fab

The monovalent antigen-binding fragment of an antibody molecule obtained when the protein is digested with the enzyme papain. It consists of an intact light chain and the immediately-associated terminal and domains of a heavy chain.
References in periodicals archive ?
Summary This report is the result of Canadean's extensive market research covering the Spirits (excluding FABs & Fort Wine) market in Latin America.
300mm Fab Will Add 50,000 Wafer Capacity; New R&D Center Nearing Completion at UMC's Southern Taiwan Site
12 South Korea Spirits (excluding FABs and Fort Wine) Volume Consumption, 2008-19 2.
However, a strong recovery of both spending types for fabs equipping and constructing is anticipated in 2008.
Sample Table of Contents - Fabs (Flavoured Alcoholic Beverages) in the United Kingdom
Hynix's selection of our Spartan Sorter for their follow-on order and new fab is yet further validation for this technology," said Paula LuPriore, vice president and general manager, software, solutions and factory interface products, of Asyst.
These declines were driven initially in part by a rise in duty levied on FABs in the April 2002 budget, which linked the duty charged on FABs to that of spirits.
Collectively, all of the new fabs coming online in 2007 will have the capacity to produce up to the equivalent of 2 million 200mm (8-inch) wafers.
Fab 36 engineers, with the help of AMD's patented Automated Precision Manufacturing (APM) systems, are constantly analyzing data collected from the test chips and making consistent improvements.
By reducing in-furnace defect generation to the lowest possible levels, fabs can realize the productivity and yield goals of advanced IC production at 300 mm while also matching the quality expectations of mature processes," Cadwell said.