Fab region | definition of Fab region by Medical dictionary
fragment antigen binding (redirected from Fab region)
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fragment antigen binding,
Area on an immunoglobulin (antibody) to which antigens bind.
References in periodicals archive
It has an extended blood half-life due to PEG moiety attached to its Fc-free Fab region
, and is effective in the treatment of RA as a subcutaneous injection either every two weeks or once a month.
One region, known as the fragment binding antigen or Fab region
, is designed to inhibit the function of a molecular structure called the epidermal growth factor receptor (EGFR), which is found on normal cells and tumor cells.
Fab-Fab, bridging of Fab regions
of immunoglobulins as a result of idiotypic antibody binding.