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Fab fragment

   Also found in: Wikipedia 0.01 sec.
Fab fragment (f-b)
n.
The portion of an immunoglobulin molecule that binds the antigen.
Fab fragment
a portion of an immunoglobulin molecule usually obtained by papain digestion, containing one light chain and part of a heavy chain with a single antigen-combining site.
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For this approach, a digoxigenin-labeled secondary antibody (antimouse FAB fragments, Chemicon, Temecula, Calif, dilution 1:500) was employed; reaction was detected by antidigoxigenin FAB fragments labeled with alkaline phosphatase (Boehringer, Mannheim, Germany, dilution 1:200) and naphthyl fast red (Research Genetics, Huntsville, Ala).
Immunohistochemical expression of galectin-3 in benign and malignant ... by Herrmann, Marille E.; LiVolsi, Virginia A.; Pasha, Theresa L.; Roberts, Shelley A.; Wojcik, Eva M.; / Archives of Pathology & Laboratory Medicine
The Dower patent covers methods to display Fab fragments using phage display technology and MorphoSys received a license for the Dower patent from Biosite in January 2000.
MorphoSys issued European patent for HuCAL antibody technology by BIOTECH Patent News
Dompe is using the technology in developing a fully human Fab fragment for radioimmunotherapy of ovarian carcinoma.
XOMA Licenses Recombinant Pharmaceutical Production Technology to ... by Business Wire
 
 
 
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