Fab


Also found in: Dictionary, Thesaurus, Financial, Acronyms, Idioms, Encyclopedia, Wikipedia.

Fab

 (fragment, antigen-binding)
originally, either of two identical fragments, each containing an antigen combining site, obtained by papain cleavage of the IgG molecule; now generally used as an adjective in terms such as Fab fragment or region, referring to an “arm” of any immunoglobulin monomer, i.e., one light chain and the adjoining heavy chain VH and CH1 domains.
digoxin immune Fab (ovine) a preparation of antigen-binding fragments derived from specific antidigoxin antibodies produced in sheep that have been immunized with digoxin coupled as a hapten to human serum albumin, used as an antidote to life-threatening digoxin and digitoxin overdose; administered intravenously.

FAB

Abbreviation for French-American-British (classification of acute leukemias). See: FAB classification.

Fab

[f ragment, a ntigen-b inding] originally, either of two identical fragments, each containing an antigen combining site, obtained by papain cleavage of the immunoglobulin IgG molecule; now generally used as an adjective to refer to an “arm” of any immunoglobulin monomer.
digoxin immune Fab (ovine)  a preparation of antigen-binding fragments derived from specific antibodies produced against digoxin in sheep; used as an antidote to digoxin and digitoxin overdose.

Fab

the fragment of an antibody molecule that contains the antigen-binding site, consisting of a light chain and part of a heavy chain. Such fragments are produced when antibodies are digested by enzymes, such as the protease papain. Fab fragments are used as an antidote for treating toxicity caused by digoxin, digitoxin, and oleander tea. See also Fc, Digibind.

Fab

Etymology: fragment, antigen-binding
originally, either of two identical fragments, each containing an antigen combining site, obtained by papain cleavage of the IgG molecule. Now it is generally used as an adjective in terms such as Fab fragment or region, referring to an "arm" of any immunoglobulin monomer, i.e., one light chain and the adjoining heavy chain VH and CH1 domains.

alcopop

A popular term for any of the alternative beverages that were formulated in response to an increase in the US federal wine tax in the early 1990s. The spirits industry responded by moving away from wine coolers to malt-based alcoholic beverages including "hard" lemonades and fruit coolers and drinks.

FANCB

A gene on chromosome Xp22.2 that encodes a protein of the Fanconi anaemia complementation group (here, complementation group B), the members of which are related not by sequence similarity, but rather by their assembly into a common nuclear protein complex.

FAB

Abbreviation for French-American-British classification system.

fab

The monovalent antigen-binding fragment of an antibody molecule obtained when the protein is digested with the enzyme papain. It consists of an intact light chain and the immediately-associated terminal and domains of a heavy chain.
References in periodicals archive ?
Problem is, America's favorite new neighbors are a team of loud, opinionated gay men: Queer Eye's Fab 5.
As fundamentalist preachers and right-wing politicians demonize and divide, the Fab 5 are doing the Lord's own work with rubber gloves, natural fabrics, and pre-shave oils: Strengthening the family.
By playing into gay stereotypes, the Fab 5, paradoxically, lay them to rest.
Since 1992, SMA has provided its subscribers with comprehensive and accurate data about all aspects of the fab business plus insight on key trends.
Quarterly Fab Report is a trademark of Strategic Marketing Associates.
Strategic Marketing Associates Reports Continuing Construction of New Fabs Will Fuel Industry Growth While Risking Overcapacity, Especially in the Memory Arena
AMD continues to also increase its operational speed, accuracy and agility using APM, which includes hundreds of AMD patented technologies that dynamically and automatically optimize fab operations.
This release contains forward-looking statements concerning Fab 36, including its production ramp, output and capacity, demand for AMD64-bit solutions, and capturing an increasing share of the x86 market, which are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995.
We are fully converting our fabs to the next technology generation at consistently accelerated rates.
Fab 12's re-opening is the latest in a string of six Intel announcements regarding re-investment in its U.
As part of the conversion project, Intel sent over 800 Fab 12 employees to other Intel fabs, including in Ireland, Oregon and New Mexico, during the construction phase to obtain advanced training on the newest tools and cutting edge 300mm technology.