FUT6

FUT6

A gene on chromosome 19p13.3 that encodes a Golgi membrane protein involved in synthesising sialyl-Lewis X, an E-selectin ligand.
 
Molecular pathology
FUT6 mutations cause fucosyltransferase-6 deficiency.
References in periodicals archive ?
Because other fucosyltransferases (FUT4, FUT6, FUT7, or FUT9) catalyze the Fuc [alpha]1,3 and [alpha]1,4 linkages to Gal residues of type 2 glycans, the [Le.
A missense mutation in the FUT6 gene results in total absence of a3-fucosylation of human a1 acid glycoprotein.