FSHR


Also found in: Acronyms.

FSHR

A gene on chromosome 2p21-p16 that encodes a G protein-coupled receptor for follicle stimulating hormone, which plays a key role in gonad development.

Molecular pathology
FSHR mutations cause ovarian dysgenesis type 1 and ovarian hyperstimulation syndrome.
References in periodicals archive ?
In all of the study groups, the relative expression of PCNA and FSHR genes as compared with the housekeeping gene (GAPDH) is shown in [Figure 3] and [Figure 4], respectively.
On the other hand, the expression levels of FSHR and PCNA were carried out by real-time RT-PCR to investigate the follicular development.
CHO cell lines stably transfected with human FSHR have been described previously (Bonomi et al.
To investigate the effects of p,p'-DDT on FSHR, we used CHO cells that were stably transfected with human FSHR (CHO-FSHR) (Bonomi et al.
The main goal of the current study was to investigate and follow the expression of both FSHR and IGF1R gene in different stages of COC development in the bovine without extracting RNA by using small number of cells as source of germ donor cells and extract these two genes from blood as a source of somatic cells to make a confirmation and comparison the results of gene expression in oocytes.
The primers for FSHR, and IFG-1R were designed using the Gene Bank sequences (accession numbers: AF176811 and X15726 respectively) according to [14] were synthesized by Shanghi Sangon Biological Engineering Technology and Services Co.
In this way the abnormal FSHR can contribute to an abnormally low response to stimulation in certain women undergoing IVF.
Future research will examine the FSHR signalling mechanisms within the cell and investigate how newly developed drugs might bypass the problems created by the genetic abnormality.
The alterations in ovarian expression of folliculogenic and steroidogenic genes were associated with significantly down-regulated FSHR mRNA expression (p < 0.
The relative abundance of the FSHR mRNA decreased in the granulosa layers from F3 to F1, but LHR mRNA displayed opposite developmental changes.