FSHR


Also found in: Acronyms.

FSHR

A gene on chromosome 2p21-p16 that encodes a G protein-coupled receptor for follicle stimulating hormone, which plays a key role in gonad development.

Molecular pathology
FSHR mutations cause ovarian dysgenesis type 1 and ovarian hyperstimulation syndrome.
References in periodicals archive ?
The primers for FSHR, and IFG-1R were designed using the Gene Bank sequences (accession numbers: AF176811 and X15726 respectively) according to [14] were synthesized by Shanghi Sangon Biological Engineering Technology and Services Co.
Thirty-five cycles of PCR were carried out with denaturation at 94[degrees]C for 30 Sec, then at annealing temperature 57[degrees]C for 30 Sec for IGF-1 and 55 [degrees]C for FSHR, and then extended at 72[degrees]C for 30 Sec.
PCR products were detected on 2 % agarose gel electrophoresis to get the fragments of FSHR and IGF-1R to use them in the cloning.
Future research will examine the FSHR signalling mechanisms within the cell and investigate how newly developed drugs might bypass the problems created by the genetic abnormality.
Expression of miRNAs predicted to target CYP19A1, FSHR, BMP4, and PCNA
Nine miRNAs for CYP19A1, three for BMP4, two for PCNA and three for FSHR were chosen for miRNA quantification.
Effect of FSH[beta] subunit on the expression of FSHR mRNA in hen
To understand the effects of the FSH[beta] subunit on the expression of FSHR mRNA in hens, semi-quantitative RT-PCR was developed to characterize expression of the FSHR gene in pituitary gland, uterus, ovary, oviduct, pancreas, glandular stomach and kidney tissues.
The primers were designed according to the cDNA sequences of chicken ESR, FSHR and GAPDH genes using Oligo 6.
02) software, Duncan's Multiple Range Test was performed to test the differences of mRNA expression of ER and FSHR among the 16 crosses.
The respective amplification programs of FSHR LHR and P450arom were as follows: 94[degrees]C, 30 s; 54[degrees]C, 60 s; 72[degrees]C, 60 s; 30 cycles; 94[degrees]C, 30 s; 54[degrees]C, 60 s; 72[degrees]C, 60 s; 23 cycles; 94[degrees]C, 30 s; 60[degrees]C, 60 s; 72[degrees]C, 60 s; 35 cycles.
In the granulosa layers of the preovulatory follicles, relative abundance of FSHR mRNA expression showed the highest level in the F3, decreased in the granulosa layers of F2, and remained low in F1.