FOSL2

(redirected from FRA2)

FOSL2

A gene on chromosome 2p23.3 that encodes a leucine zipper DNA-binding FOS-type nuclear phosphoprotein, which dimerises with proteins of the JUN family to form the transcription factor complex AP1. FOS proteins regulate cell proliferation, differentiation and transformation, and may be associated with apoptosis. FOSL2 controls osteoclast survival and size; it forms a heterodimer with JUN, activates LIF transcription and activates CEBPB transcription in PGE2-activated osteoblasts.
References in periodicals archive ?
EIS measurements were performed using a potentiostat/galvanostat (AutoLab EcoChemie PGSTAT30) equipped with a FRA2 frequency response analyzer module in a classic three-electrode cell with a working area of 9.
14]C [+ or -] Stratum Unit FRA1 80104/11206 32110 330 R FAS 217 FRA2 09381/15334 33250 420 Q FAS 221 Raw radiocarbon dat Calibrated date (cal BP) 68.
The EIS measurements were carried out with Autolab PGSTAT 302N Potentiosat/Galvanostat and FRA2 frequency response analyzer at open circuit potential with AC amplitude of 20 mV over a frequency ranging from 100 kHz to 1 mHz.