FOXO6

FOXO6

A gene on chromosome 1p34.2 that encodes a member of the forkhead family of transcription factors.
References in periodicals archive ?
FOXO is a subfamily of Forkhead Box (FOX) transcription factors, and is further divided into FOXO1, FOXO3, FOXO4 and FOXO6 (Maiese et al.
It is active in most cells and is very similar to human FOXO1, FOXO3, FOXO4 and FOXO6 genes.
In addition, an abundance of evidences suggest that three members of the FOXO subfamily--FOXO1, FOXO3, and FOXO4--are critical in maintaining cardiac function and mediating cardiac stresses in the adult (the remaining FOXO family member, FOXO6, is localized in the brain) [32].
It is though that ROS accumulation could promote cancer progression via the activation of several transcriptional factors, including FOXO6, regulating the expression of cell cycle genes (i.