FOLFOX


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FOLFOX

Oxaliplatin, leucovorin, and fluorouracil, chemotherapeutic drugs used to treat cancers of the intestine, pancreas, and stomach, among other organs.
References in periodicals archive ?
The patients were randomized into 3 groups, namely, 57 cases in the group that received chemotherapy with FOLFOX (group A), 35 cases treated with chemotherapy plus invasive treatment (group B) and 31 cases treated with chemotherapy plus hyperthermia treatment that lasted one hour (group C).
Patients who received panitumumab plus FOLFOX and were then treated with aVEGF inhibitor-based treatment (including bevacizumab) had a median OS improvement of 41.
Prognostic implication of mucinous histology in colorectal) cancer patients treated: with adjuvant FOLFOX chemotherapy Br J Cancer 2013; 108:1978-84;
Here, substantial progress is more difficult to detect, especially if we look for increased overall survival when new drugs are added to standard chemotherapy regimens (such as the FOLFOX and FOLFIRI).
Oxaliplatin (Eloxatin): For the treatment of advanced colorectal cancer, oxaliplatin is usually given together with 5-FU and leucovorin (known as the FOLFOX regimen) or with capecitabine (known as the CapeOX regimen) as a first- or second-line treatment.
Patients with advanced bowel cancer are normally given a treatment called FOLFOX which combines three chemotherapy drugs.
COIN is a first-line colorectal cancer study, similar to the original CRYSTAL study using cetuximab in first-line colorectal cancer [3], but using different chemotherapy backbones, and there were two comparisons: standard therapy of FOLFOX or XELOX with or without cetuximab [4] as well as continuous versus intermittent therapy [5].
K-RAS status and efficacy of first-line treatment of patients with metastatic colorectal cancer (mCRC) with FOLFOX with or without cetuximab: The OPUS experience.
It was also absolutely clear that FOLFOX was completely ineffective in my case.
For example, the FOLFOX regimen (Fluorouracil, leucovorin, and oxaliplatin) costs nearly $12,000 dollars for an 8-week course compared to approximately $21,000 for FOLFOX combined with the antibody drug bevacizumab, but the combination with antibody drug results in a significant increased benefit in the median survival time.
43) Oxaliplatin-based combination chemotherapy, referred to as FOLFOX, appears to offer superior efficacy for patients with resected stage II and stage III colon cancer and likely will replace 5-FU and leucovorin chemotherapy as the preferred treatment for many patients in coming years.