ITGB1

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ITGB1

A gene on chromosome 10p11.2 that encodes an integrin beta chain protein, which forms part of receptors (with different alpha chains) for collagen, fibronectin, fibrinogen, laminin, VCAM1, cytotactin, osteopontin, vitronectin, epiligrin, thrombospondin and CSPG4. It is involved in embryogenesis, haemostasis, tissue repair, immune response and metastatic spread of malignant cells.