In order to perform GWAS study for identifying FMDV
resistant loci in cattle, we collected a total of 96 female Holstein (26 infected and 70 resistant animals) reared in four field dairy farms which have been affected by FMD and some of the animals were found to be infected (Table 1).
In 2013, as part of a study of FMDV
transmission between wildlife, especially African buffalo (Syncerus caffer), and domestic animals, 20 long-horned Ankole cattle ([approximately equal to] 6 months of age) were introduced as sentinel animals into Nyakatonzi (Kasese District), in close proximity to the QENP.
Was the outbreak caused by the FMDV
used to challenge vaccinated animals, either the strain from Porton Down or the virulent strain resulting from serial passage in pigs which has escaped from one of the labs?
FMD-positive test results were confirmed on November 28-29 (Table 1) in samples from saliva, vesicles, and detached hooves from pigs with signs typical of FMDV
During 2009-2010, the geographic range of 2 FMDV
lineages endemic to Southeast Asia (serotypes A and O) expanded into eastern Asia and caused outbreaks in 6 countries in the region.
During 1988-1991, analysis of outbreak samples from Ethiopia at the National Veterinary Institute (NVI), Debre Zeit, Ethiopia, and at the Food and Agriculture Organization World Reference Laboratory for Foot-and-Mouth Disease (WRLFMD), Institute for Animal Health, Pirbright, UK, identified serotype O and serotype SAT 2 FMDV
as the causative agents (9).
is highly contagious, and this, together with its ability to infect different hosts and to exist as multiple types and variants, makes FMD difficult to control and a severe constraint to international trade of livestock and their products.
inactivate the virus that causes foot and mouth disease (FMDV
On February 15, 2006, the Agriculture Ministry in Egypt notified international public health authorities (by reporting to the World Organization for Animal Health [OIE]) of 6 outbreaks of FMDV
caused by serotype A in Ismailia and 12 additional outbreaks in 7 other Egyptian governorates: Alexandria (2 outbreaks), Behera (1 outbreak), Cairo (1 outbreak), Dakahlia (1 outbreak), Dumyat (5 outbreaks), Fayum (1 outbreak), and Menofia (1 outbreak).
is a member of the class of non-enveloped viruses, which are known to be resistant to many chemical inactivation agents and is therefore useful as a model to evaluate virucidal robustness.
This is the first report of Dhori virus isolation in East Africa and the first known isolation of FMDV
associated with tick collection.
A pandemic such as this is a rare phenomenon but demonstrates the ability of newly emerging FMDV
strains to spread rapidly throughout a wide region and invade countries previously free from the disease.