FLT4


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FLT4

A gene on chromosome 5q35.3 that encodes a tyrosine kinase receptor for vascular endothelial growth factors (VEGF) C and D, which appear to play a role in lymphangiogenesis and maintenance of the lymphatic endothelium.

Molecular pathology
FLT4 mutations cause hereditary lymphedema type IA.
References in periodicals archive ?
Consistent MYC and FLT4 gene amplification in radiation-induced angiosarcoma but not in other radiation-associated atypical vascular lesions.