FLNA

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FLNA

A gene on chromosome Xq28 that encodes filamin A, an actin-binding protein which crosslinks actin filaments, binding them to membrane glycoproteins. Filamin A is involved in remodelling the cytoskeleton to effect changes in cell shape and migration; it interacts with integrins, transmembrane receptor complexes and second messengers.

Molecular pathology
Defects in FLNA cause:
• Cardiac valvular dysplasia X-linked;
• Frontometaphyseal dysplasia;
• Melnick-Needles syndrome;
• Otopalatodigital syndromes types 1 and 2;
• Periventricular nodular heterotopia types 1 and 4; and
• Terminal osseous dysplasia.
Defects may also cause macrothrombocytopaenia.
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He also expressed his consideration to the FLN for its efforts to strengthen the ties binding it to the Rally, through the exchange of visits and the presence of FLN representatives in the RCD Congresses
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Foreign affairs expert Hilaire du Berrier, in the late 1950s, and later in American Opinion, revealed how the Soviet KGB created the FLN movement in Algeria to break away that portion of France and install a communist regime.
The main candidates are President Bouteflika and former prime minister Ali Benflis, who is currently the secretary general of the FLN to which the president belongs, as well as being a former ally of the president.