FLNA

(redirected from FLN)
Also found in: Dictionary, Acronyms, Wikipedia.

FLNA

A gene on chromosome Xq28 that encodes filamin A, an actin-binding protein which crosslinks actin filaments, binding them to membrane glycoproteins. Filamin A is involved in remodelling the cytoskeleton to effect changes in cell shape and migration; it interacts with integrins, transmembrane receptor complexes and second messengers.

Molecular pathology
Defects in FLNA cause:
• Cardiac valvular dysplasia X-linked;
• Frontometaphyseal dysplasia;
• Melnick-Needles syndrome;
• Otopalatodigital syndromes types 1 and 2;
• Periventricular nodular heterotopia types 1 and 4; and
• Terminal osseous dysplasia.
Defects may also cause macrothrombocytopaenia.
References in periodicals archive ?
By and large, a 35 per cent turnout can be considered reasonable, but the FLN government and its allies should watch out for the seething state of the Algerian street, with the underlying frustrations across social strata - affecting not just the poor and the middle classes, but also the young.
From Bouteflika's perspective, this is thanks to his younger brother/physician, Dr Said, an exceptionally intelligent but corrupt figure who is controversial, PM AbdelMalek Sellal and FLN Secretary-General Amar Sa'dani.
Should he announce he will run again, Bouteflika, who has governed Algeria since 1999, will almost certainly win due to the FLN nationalist party's dominant role and his backing from the party's machinery and its allies.
This type of sporting nationalism, underlining the need for fit and healthy bodies to fight French rule, marked a generation of nationalists who formed the FLN in 1954.
However, it was not an easy choice for the players: Maouche was doing his military service in the French army and risked prison for desertion, Zitouni would have to forgo the World Cup and his transfer to Real, some of the players were married to French women, and the salaries offered by the FLN did not compare with the money their clubs paid.
Contrasting the strict celibacy of FLN members with the debauchery of their Foreign Legion opponents, who included former Nazis and routinely patronized prostitutes, the author depicts Col Mesniere de Schacken, a French intelligence officer assassinated by the FLN, as the epitome of a villainous Frenchman.
The main candidates are President Bouteflika and former prime minister Ali Benflis, who is currently the secretary general of the FLN to which the president belongs, as well as being a former ally of the president.
The draft had been debated and revised several times since 2000 to satisfy the old guard in the dominant FLN Party (see Gas Market Trends No.
The FLN won 199 seats in the new 389-seat assembly.
On LT exposure, vernalization-requiring plants continue to reduce their FLN up to the point of vernalization saturation (Wang et al.
Despues de cerca de 20 anos de trabajar en la clandestinidad como comandante en jefe de las Fuerzas de Liberacion Nacional (FLN), primero, y del Ejercito Zapatista de Liberacion Nacional, despues, y tambien como secretario general del Partido de las FLN (PFLN), el arquitecto Fernando Yanez Munoz, comandante German, por primera vez actuara publicamente al lado del subcomandante Marcos.
He was brought in to run for the presidency backed by the military and the FLN.