MPP5

(redirected from FLJ12615)

MPP5

A gene on chromosome 14q23.3 that encodes palmitoylated membrane protein 5, a member of the membrane-associated guanylate kinase homologs (MAGUK) family. MAGUKs interact with the cytoskeleton, regulating cell proliferation, signalling pathways and intracellular junctions; they are involved in tumour suppression and receptor clustering by forming multiprotein complexes with distinct sets of transmembrane, cytoskeletal and cytoplasmic-signalling proteins.