RETN

(redirected from FIZZ3)

RETN

A gene on chromosome 19p13.2 that encodes resistin, which is secreted by adipocytes and suppresses insulin-driven glucose uptake by adipose cells.

Molecular pathology
RETN mutations may link obesity to type-2 diabetes.
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References in periodicals archive ?
The third homolog, FIZZ3, is known as resistin or adipocyte-specific secretory factor and is identical to the fat specific homolog (119).
FIZZ3 is produced in adipose tissue and was shown to antagonize insulin action.