FGF12

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FGF12

A gene on chromosome 3q28 that encodes fibroblast growth factor 12 of the FGF family, which bind heparin and have a broad range of cellular activities, including cell survival, division, differentiation and migration, embryonic development, morphogenesis, tissue repair, tumour growth and invasion. FGF12’s function is unknown; it lacks the N-terminal signal sequence found in most other FGF family members, but has clusters of basic residues which act as a nuclear localisation signal. It is highly expressed in embryonic retina, olfactory epithelium, olfactory bulb, and segmentally in the body wall. It is thought to play a role in nervous system development and function.
References in periodicals archive ?
We matched both to the BLS category FHF1 "fresh fruits," on the following two assumptions: Consumer tastes for most fruits are similar, therefore consumer behavior for a more disaggregated fruit (bananas) should closely match the consumer behavior for aggregate fruit; furthermore, most trade is likely to be in fresh fruit, the part in which the BLS and SITC descriptions coincide.