FGF14


Also found in: Acronyms.

FGF14

A gene on chromosome 13q34 that encodes fibroblast growth factor 14 of the FGF family, which bind heparin and have a broad range of cellular activities, including cell survival, division, differentiation and migration, embryonic development, morphogenesis, tissue repair, tumour growth and invasion. FGF14’s function is unknown; it is thought to play a role in nervous system development and function.

Molecular pathology
FXF14 mutations cause (autosomal dominant) spinocerebellar ataxia type 27.
References in periodicals archive ?
Survival tree analysis revealed FGF2, FGFR2, FGFR4, FGF14, and FGF23 gene- gene interactions, indicating FGF2 rs167428 to be the primary factor contributing to overall survival.
6] Human genes: FGF2, fibroblast growth factor 2 (basic); FGF1, fibroblast growth factor 1 (acidic); FGF7, fibroblast growth factor 7; FGFR1, fibroblast growth factor receptor1; FGF18, fibroblast growth factor 18; FGF23, fibroblast growth factor 23; FGF5, fibroblast growth factor 5; FGFR2, fibroblast growth factor receptor 2; FGFR4, fibroblast growth factor receptor 4; FGF14, fibroblast growth factor 14; FGF9, fibroblast growth factor 9; FGF10, fibroblast growth factor 10.