FGF12

FGF12

A gene on chromosome 3q28 that encodes fibroblast growth factor 12 of the FGF family, which bind heparin and have a broad range of cellular activities, including cell survival, division, differentiation and migration, embryonic development, morphogenesis, tissue repair, tumour growth and invasion. FGF12’s function is unknown; it lacks the N-terminal signal sequence found in most other FGF family members, but has clusters of basic residues which act as a nuclear localisation signal. It is highly expressed in embryonic retina, olfactory epithelium, olfactory bulb, and segmentally in the body wall. It is thought to play a role in nervous system development and function.
References in periodicals archive ?
56E-05 Plumage part rs ID Gene Location Head rs14398623 RNF144A Intron rs318020030 PPP1R9B Intron rs16669242 FGF12 Intergenic GGaluGA105119 ENSGALG000 Intergenic 00023628 rs14112979 HELZ Intron Wing rs13982792 XPO4 Intron rs14131527 XIRP1 Intron rs14188826 PRL Intergenic rs14339964 AKT3 Intron rs14404313 NT5C1B Intergenic GGaluGA110134 MSI1 Intron rs15027075 PBX3 Intron Breast rs14316836 LCLAT1 Intron Back rs14401050 E2F6 Intergenic rs15616451 ENSGALG000 Intergenic 00020136 GGaluGA287070 VRK1 Intergenic GGaluGA095084 SGCD Intron rs15022353 TTC28 Intron (1) Minor allele/Major allele.