FGD1

FGD1

A gene on chromosome p11.21, which encodes a protein that contains Dbl and pleckstrin homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen-activated protein-kinase cascade, leading to c-Jun kinase SAPK/JNK1 activation.
References in periodicals archive ?
The belief that they had been able to conceive by taking the medicines from TH was echoed by many participants of both FGD1 and FGD2, including educated, semi-educated and uneducated participants.
The same belief of getting the tidal water for easing the process of the delivery was echoed among the participants of FGD1.
In this connection, the participants of FGD1 stated that their new born child will be taken away by 'Chora Chunni' (mythical malicious spirits) if they do not stay in-door for forty days.