MLH1

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MLH1

A human homologue of the Escherichia coli DNA mismatch repair gene on 3p21.3, which encodes an enzyme that scans newly replicated DNA for errors and repairs mismatched base pairs.

Molecular pathology
A germline mutation of MLH1 occurs in ± 1% of patients with hereditary nonpolyposis colon cancer; defects in MLH1 also cause mismatch repair cancer syndrome, Muir-Torre syndrome and susceptibility to endometrial cancer.
References in periodicals archive ?
Vehicle emission factors were developed for winter (55[degrees]F/50% relative humidity) and summer (75[degrees]F/50% relative humidity) conditions using average speeds of 65 mph on freeways and high-ways [FCC (functional class code) 1 and FCC2 class roads], 50 mph on major arterials (FCC3 class roads), and 30 mph on minor arterials and collectors (FCC4 roads).
reputed as having captured the FCC2 (260)--asked the FCC to rule that
KEY: FCC2 (Frizzel County Championship, Division Two); TSL2 (totesport League, Division Two); C&G (Cheltenham & Gloucester Trophy); Twenty20 (Twenty20 Cup); TOM (tour match); UNI/UCCE (University Cricketing Centre of Excellence).
Fri 1: Leicestershire (home) T20; Sun 3: Lancashire (away) T20; Mon 4: Yorkshire (home) T20; Wed 6: Lancashire (home) T20; Fri 8: Lancashire (home) FCC2; Sun 17: Warwickshire (home) TSL2; Wed 20: Derbyshire (away) TSL2: Thur 21: Derbyshire (away) FCC2; Tue 26: Somerset (away) FCC2.
Wed 3: Essex (away) FCC2; Sun 7: Bangladesh A (home) TOM; Fri 12: Leicestershire (home) FCC2; Tue 16: Leicestershire (home) TSL2; Sun 21: Somerset (away) TSL2; Wed 24: Yorkshire (away) FCC2; Sun 28: Scotland (home) TSL2; Tue 30: Derbyshire (home) FCC2.
Alcoa's AFL Telecommunications announces the release of its FCC2 Fiber Connector Cleaner, and Connector Cleaning Tips.
The FCC2 Fiber Connector Cleaner is a non-flammable, environmentally safe, residue free solvent designed to clean fiber connector end faces.